The association between antidepressant treatment and neuropathologic changes of Lead Investigator: Fang Han Institution : Beijing University of Chinese Medicinec E-Mail : h8770244@uw.edu Proposal ID : 929 Proposal Description: Prior studies reported that antidepressant treatment was associated with increased risk of dementia, including Alzheimer disease(AD). However, there is no evidence whether the antidepressant use will have effects on neuropathologic changes of AD. Our We aim to examine whether the antidepressant use is associated with ADNC using NACC data.